Zhang, T <br/><br/>
Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major.  [electronic resource] 

 -  Biochemical and biophysical research communications  Sep 2000 
 - 693-701 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-291X 
<br/><br/><label>Standard No.: </label>10.1006/bbrc.2000.3538  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibody Formation--drug effects<br/>Antigen Presentation--immunology<br/>Antigen-Presenting Cells--immunology<br/>Antigens, Differentiation, B-Lymphocyte--immunology<br/>Antigens, Protozoan--metabolism<br/>Aspartic Acid Endopeptidases--antagonists & inhibitors<br/>CD4-Positive T-Lymphocytes--drug effects<br/>Cathepsin B--antagonists & inhibitors<br/>Cell Division--drug effects<br/>Cysteine Proteinase Inhibitors--therapeutic use<br/>Cytokines--metabolism<br/>Dipeptides--therapeutic use<br/>Disease Models, Animal<br/>Female<br/>Histocompatibility Antigens Class II--immunology<br/>Leishmania major<br/>Leishmaniasis, Cutaneous--drug therapy<br/>Lymphocytes--drug effects<br/>Lysosomes--metabolism<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Inbred DBA<br/>Pepstatins--pharmacology<br/>Th1 Cells--drug effects<br/>Th2 Cells--drug effects