Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease. [electronic resource]
- The Journal of neuroscience : the official journal of the Society for Neuroscience Oct 2000
- 7505-9 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1529-2401
Aged Aged, 80 and over Alzheimer Disease--immunology Amyloid beta-Peptides--pharmacology CD59 Antigens--genetics Cell Differentiation--drug effects Cell Survival--drug effects Cells, Cultured Complement C9--genetics Complement System Proteins--pharmacology Dose-Response Relationship, Drug Female Frontal Lobe--metabolism Gene Expression--drug effects Glycosylphosphatidylinositols--metabolism Hippocampus--metabolism Humans Male Neurons--drug effects Peptide Fragments--pharmacology Phosphatidylinositol Diacylglycerol-Lyase Phosphopyruvate Hydratase--metabolism RNA, Messenger--metabolism Ribonucleases--deficiency Synaptophysin--metabolism Transfection Type C Phospholipases--antagonists & inhibitors