Yang, L B

Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Oct 2000 - 7505-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1529-2401


Aged
Aged, 80 and over
Alzheimer Disease--immunology
Amyloid beta-Peptides--pharmacology
CD59 Antigens--genetics
Cell Differentiation--drug effects
Cell Survival--drug effects
Cells, Cultured
Complement C9--genetics
Complement System Proteins--pharmacology
Dose-Response Relationship, Drug
Female
Frontal Lobe--metabolism
Gene Expression--drug effects
Glycosylphosphatidylinositols--metabolism
Hippocampus--metabolism
Humans
Male
Neurons--drug effects
Peptide Fragments--pharmacology
Phosphatidylinositol Diacylglycerol-Lyase
Phosphopyruvate Hydratase--metabolism
RNA, Messenger--metabolism
Ribonucleases--deficiency
Synaptophysin--metabolism
Transfection
Type C Phospholipases--antagonists & inhibitors