Blaskovich, M A <br/><br/>
Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice.  [electronic resource] 

 -  Nature biotechnology  Oct 2000 
 - 1065-70 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1087-0156 
<br/><br/><label>Standard No.: </label>10.1038/80257  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Angiogenesis Inhibitors--chemistry<br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Cell Division--drug effects<br/>Cell Line<br/>DNA--biosynthesis<br/>Drug Design<br/>Endothelial Growth Factors--antagonists & inhibitors<br/>Enzyme Activation--drug effects<br/>Glioblastoma--blood supply<br/>Humans<br/>Inhibitory Concentration 50<br/>Lymphokines--antagonists & inhibitors<br/>Mice<br/>Mice, Nude<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Neoplasm Transplantation<br/>Neovascularization, Pathologic--drug therapy<br/>Peptides, Cyclic--chemistry<br/>Phosphorylation--drug effects<br/>Platelet-Derived Growth Factor--antagonists & inhibitors<br/>Receptor Protein-Tyrosine Kinases--metabolism<br/>Receptors, Growth Factor--metabolism<br/>Receptors, Platelet-Derived Growth Factor--antagonists & inhibitors<br/>Receptors, Vascular Endothelial Growth Factor<br/>Substrate Specificity<br/>Vascular Endothelial Growth Factor A<br/>Vascular Endothelial Growth Factors