Chua, M S

Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells. [electronic resource] - Cancer research Sep 2000 - 5196-203 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0008-5472


Aniline Compounds--metabolism
Antineoplastic Agents--metabolism
Aryl Hydrocarbon Hydroxylases
Benzoflavones--pharmacology
Benzothiazoles
Breast Neoplasms--drug therapy
Cytochrome P-450 CYP1A1--antagonists & inhibitors
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System--metabolism
Drug Interactions
Enzyme Inhibitors--pharmacology
Humans
Hydroxylation
Isoenzymes--antagonists & inhibitors
Mixed Function Oxygenases--biosynthesis
Protein Binding
Substrate Specificity
Thiazoles--metabolism
Tumor Cells, Cultured