Arnold, L D <br/><br/>
Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Oct 2000 
 - 2167-70 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/s0960-894x(00)00441-8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Drug Design<br/>Enzyme Inhibitors--chemical synthesis<br/>Humans<br/>Jurkat Cells<br/>Lymphocyte Specific Protein Tyrosine Kinase p56(lck)--antagonists & inhibitors<br/>Models, Molecular<br/>Molecular Structure<br/>Proto-Oncogene Proteins pp60(c-src)--antagonists & inhibitors<br/>Pyrimidines--chemical synthesis<br/>Pyrroles--chemical synthesis<br/>Receptor Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Receptor, TIE-2<br/>Receptors, Growth Factor--antagonists & inhibitors<br/>Receptors, Vascular Endothelial Growth Factor<br/>Substrate Specificity