TY  - GEN
AU  - Michael,W M
AU  - Ott,R
AU  - Fanning,E
AU  - Newport,J
TI  - Activation of the DNA replication checkpoint through RNA synthesis by primase
SN  - 0036-8075
PY  - 2000///1010
KW  - Animals
KW  - Aphidicolin
KW  - pharmacology
KW  - CDC2-CDC28 Kinases
KW  - Carrier Proteins
KW  - metabolism
KW  - Checkpoint Kinase 1
KW  - Chromatin
KW  - Cyclin E
KW  - Cyclin-Dependent Kinase 2
KW  - Cyclin-Dependent Kinases
KW  - DNA Helicases
KW  - DNA Polymerase I
KW  - antagonists & inhibitors
KW  - DNA Primase
KW  - DNA Replication
KW  - drug effects
KW  - DNA, Single-Stranded
KW  - DNA-Binding Proteins
KW  - Mitosis
KW  - Nuclear Proteins
KW  - Phosphorylation
KW  - Protein Kinases
KW  - Protein Serine-Threonine Kinases
KW  - RNA
KW  - biosynthesis
KW  - Recombinant Proteins
KW  - S Phase
KW  - Saccharomyces cerevisiae Proteins
KW  - Signal Transduction
KW  - Xenopus
KW  - Xenopus Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1126/science.289.5487.2133
ER  -