Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Oct 2000
- 373-81 p. digital
Publication Type: Journal Article
0022-3565
Animals Brain--drug effects CHO Cells Calcium--metabolism Cricetinae Dose-Response Relationship, Drug Humans In Vitro Techniques Iris--drug effects Male Mice Mice, Inbred BALB C Peptide Fragments--pharmacology Quinolines--pharmacokinetics Rabbits Rats Rats, Sprague-Dawley Receptors, Neurokinin-3--antagonists & inhibitors Substance P--analogs & derivatives