Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. [electronic resource]
- Cancer research Sep 2000
- 4881-8 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0008-5472
Abnormalities, Multiple--genetics Ataxia Telangiectasia--genetics Cell Cycle--physiology Cell Line Cell Survival--radiation effects Checkpoint Kinase 2 Chromosome Breakage Chromosomes, Human--radiation effects DNA--radiation effects DNA Damage DNA Repair Fibroblasts--pathology Humans Interphase--genetics Mitosis--genetics Phosphorylation Protein Kinases--metabolism Protein Serine-Threonine Kinases Radiation Tolerance--genetics Syndrome Tumor Suppressor Protein p53--biosynthesis