TY  - GEN
AU  - Xiong,L
AU  - Kloss,P
AU  - Douthwaite,S
AU  - Andersen,N M
AU  - Swaney,S
AU  - Shinabarger,D L
AU  - Mankin,A S
TI  - Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action
SN  - 0021-9193
PY  - 2000///1024
KW  - Acetamides
KW  - chemistry
KW  - Amino Acid Substitution
KW  - Anti-Bacterial Agents
KW  - Base Sequence
KW  - Binding Sites
KW  - Catalysis
KW  - Catalytic Domain
KW  - Drug Resistance, Microbial
KW  - Escherichia coli
KW  - drug effects
KW  - Genes, Bacterial
KW  - Genetic Engineering
KW  - Linezolid
KW  - Molecular Sequence Data
KW  - Molecular Structure
KW  - Mutagenesis
KW  - Nucleic Acid Conformation
KW  - Oxazolidinones
KW  - Peptidyl Transferases
KW  - metabolism
KW  - RNA, Bacterial
KW  - RNA, Ribosomal, 23S
KW  - Ribosomes
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1128/JB.182.19.5325-5331.2000
ER  -