TY  - GEN
AU  - Weiss,K K
AU  - Isaacs,S J
AU  - Tran,N H
AU  - Adman,E T
AU  - Kim,B
TI  - Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions
SN  - 0006-2960
PY  - 2000///0928
KW  - Amino Acid Substitution
KW  - genetics
KW  - Anti-HIV Agents
KW  - pharmacology
KW  - Base Pair Mismatch
KW  - Binding Sites
KW  - DNA Mutational Analysis
KW  - DNA Primers
KW  - chemistry
KW  - Dideoxynucleotides
KW  - Glutamine
KW  - Glycine
KW  - HIV Reverse Transcriptase
KW  - antagonists & inhibitors
KW  - Humans
KW  - Lac Operon
KW  - Lysine
KW  - Mutagenesis, Site-Directed
KW  - Protein Processing, Post-Translational
KW  - Protein Structure, Secondary
KW  - RNA
KW  - Substrate Specificity
KW  - Templates, Genetic
KW  - Thymine Nucleotides
KW  - Tryptophan
KW  - Zidovudine
KW  - analogs & derivatives
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/bi000788y
ER  -