Krieger-Brauer, H I

Basic fibroblast growth factor utilizes both types of component subunits of Gs for dual signaling in human adipocytes. Stimulation of adenylyl cyclase via Galph(s) and inhibition of NADPH oxidase by Gbeta gamma(s). [electronic resource] - The Journal of biological chemistry Nov 2000 - 35920-5 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M002490200 doi


Adenylyl Cyclase Inhibitors
Adenylyl Cyclases--metabolism
Adipocytes--drug effects
Antibodies--pharmacology
Cell Membrane--drug effects
Cyclic AMP-Dependent Protein Kinases--pharmacology
Fibroblast Growth Factor 1--pharmacology
Fibroblast Growth Factor 2--pharmacology
GTP-Binding Protein alpha Subunits, Gs--antagonists & inhibitors
Guanosine 5'-O-(3-Thiotriphosphate)--pharmacology
Humans
Hydrogen Peroxide--metabolism
Insulin--pharmacology
NADPH Oxidases--antagonists & inhibitors
Peptide Fragments--pharmacology
Receptor Protein-Tyrosine Kinases--metabolism
Recombinant Proteins
Signal Transduction--drug effects