TY - GEN AU - Walker,V E AU - Wu,K Y AU - Upton,P B AU - Ranasinghe,A AU - Scheller,N AU - Cho,M H AU - Vergnes,J S AU - Skopek,T R AU - Swenberg,J A TI - Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide SN - 0143-3334 PY - 2000///1002 KW - Animals KW - Biomarkers KW - analysis KW - Biotransformation KW - Carcinogens KW - pharmacokinetics KW - DNA KW - drug effects KW - DNA Damage KW - Dose-Response Relationship, Drug KW - Ethylene Oxide KW - metabolism KW - Ethylenes KW - Guanine KW - analogs & derivatives KW - Hemoglobins KW - Hypoxanthine Phosphoribosyltransferase KW - genetics KW - Inhalation Exposure KW - Male KW - Mice KW - Mice, Inbred Strains KW - Mutation KW - Rats KW - Rats, Inbred F344 KW - T-Lymphocytes KW - enzymology KW - Valine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1093/carcin/21.9.1661 ER -