The importance of reactant positioning in enzyme catalysis: a hybrid quantum mechanics/molecular mechanics study of a haloalkane dehalogenase. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Aug 2000
- 9937-42 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
0027-8424
10.1073/pnas.97.18.9937 doi
Acetates--chemistry Amino Acid Sequence Aspartic Acid Binding Sites Calorimetry Catalysis Enzymes--chemistry Ethylene Dichlorides--chemistry Hydrolases--chemistry Models, Chemical Models, Molecular Molecular Conformation Protein Conformation Quantum Theory Xanthobacter--enzymology