Kalgutkar, A S

Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. [electronic resource] - Journal of medicinal chemistry Jul 2000 - 2860-70 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm000004e doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis
Cell Line
Cyclooxygenase 1
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--chemical synthesis
Humans
Indomethacin--analogs & derivatives
Isoenzymes--antagonists & inhibitors
Macrophages--drug effects
Membrane Proteins
Mice
Prostaglandin-Endoperoxide Synthases--chemistry
Sheep
Structure-Activity Relationship