TY  - GEN
AU  - Arris,C E
AU  - Boyle,F T
AU  - Calvert,A H
AU  - Curtin,N J
AU  - Endicott,J A
AU  - Garman,E F
AU  - Gibson,A E
AU  - Golding,B T
AU  - Grant,S
AU  - Griffin,R J
AU  - Jewsbury,P
AU  - Johnson,L N
AU  - Lawrie,A M
AU  - Newell,D R
AU  - Noble,M E
AU  - Sausville,E A
AU  - Schultz,R
AU  - Yu,W
TI  - Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
SN  - 0022-2623
PY  - 2000///0905
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - CDC2 Protein Kinase
KW  - antagonists & inhibitors
KW  - CDC2-CDC28 Kinases
KW  - Crystallography, X-Ray
KW  - Cyclin-Dependent Kinase 2
KW  - Cyclin-Dependent Kinases
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Hydrogen Bonding
KW  - Models, Molecular
KW  - Protein Serine-Threonine Kinases
KW  - Purines
KW  - Pyrimidines
KW  - Structure-Activity Relationship
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm990628o
ER  -