Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Aug 2000
- 9984-9 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.180194597 doi
Animals Blood Platelets--drug effects Brain--drug effects Cocaine--pharmacology Collagen--pharmacology Cyclic AMP--blood Epinephrine--pharmacology GTP-Binding Protein alpha Subunits Heterotrimeric GTP-Binding Proteins--deficiency Humans Lung--drug effects Male Mice Mice, Knockout Morphine--pharmacology Motor Activity Platelet Activation--physiology Platelet Aggregation Psychotropic Drugs--pharmacology Signal Transduction Thromboembolism--genetics