TY - GEN AU - Srinivasula,S M AU - Datta,P AU - Fan,X J AU - Fernandes-Alnemri,T AU - Huang,Z AU - Alnemri,E S TI - Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway SN - 0021-9258 PY - 2000///1229 KW - Amino Acid Sequence KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - Bacterial Proteins KW - antagonists & inhibitors KW - Carrier Proteins KW - chemistry KW - Caspase Inhibitors KW - Caspases KW - metabolism KW - Cell Differentiation KW - Cytosol KW - Enzyme Activation KW - Humans KW - Inhibitor of Apoptosis Proteins KW - Insect Proteins KW - Intracellular Signaling Peptides and Proteins KW - Membrane Glycoproteins KW - Mitochondria KW - Mitochondrial Proteins KW - Molecular Sequence Data KW - Mutation KW - genetics KW - Protein Binding KW - Protein Isoforms KW - Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Receptors, Tumor Necrosis Factor KW - Signal Transduction KW - TNF-Related Apoptosis-Inducing Ligand KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Necrosis Factor-alpha KW - X-Linked Inhibitor of Apoptosis Protein KW - bcl-X Protein N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.C000533200 ER -