Wurzer, G <br/><br/>
Increased resistance to anticancer therapy of mouse cells lacking the poly(ADP-ribose) polymerase attributable to up-regulation of the multidrug resistance gene product P-glycoprotein.  [electronic resource] 

 -  Cancer research  Aug 2000 
 - 4238-44 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--antagonists & inhibitors<br/>Animals<br/>Antineoplastic Agents--pharmacokinetics<br/>Breast Neoplasms--drug therapy<br/>Clone Cells<br/>Dose-Response Relationship, Drug<br/>Doxorubicin--pharmacokinetics<br/>Drug Resistance, Multiple--genetics<br/>Drug Resistance, Neoplasm--genetics<br/>Embryo, Mammalian<br/>Fibroblasts--drug effects<br/>Gene Expression Regulation--drug effects<br/>Gene Expression Regulation, Neoplastic<br/>Humans<br/>Mice<br/>Mice, Knockout<br/>Poly(ADP-ribose) Polymerases--deficiency<br/>Probenecid--pharmacology<br/>Tumor Cells, Cultured<br/>Tumor Suppressor Protein p53--biosynthesis<br/>Up-Regulation<br/>Verapamil--pharmacology