TY  - GEN
AU  - Farzan,M
AU  - Schnitzler,C E
AU  - Vasilieva,N
AU  - Leung,D
AU  - Choe,H
TI  - BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein
SN  - 0027-8424
PY  - 2000///0919
KW  - Alzheimer Disease
KW  - genetics
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Peptides
KW  - chemistry
KW  - Amyloid beta-Protein Precursor
KW  - Arginine
KW  - Aspartic Acid Endopeptidases
KW  - Binding Sites
KW  - Cell Line
KW  - Cloning, Molecular
KW  - Endopeptidases
KW  - Gene Expression Profiling
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Molecular Sequence Data
KW  - Mutation, Missense
KW  - Nervous System
KW  - enzymology
KW  - Netherlands
KW  - Peptide Fragments
KW  - Phenylalanine
KW  - metabolism
KW  - Protein Processing, Post-Translational
KW  - RNA, Messenger
KW  - analysis
KW  - Recombinant Fusion Proteins
KW  - Sequence Homology, Amino Acid
KW  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
KW  - Substrate Specificity
KW  - Sweden
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1073/pnas.160115697
ER  -