Farzan, M
BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Aug 2000
- 9712-7 p. digital
Publication Type: Journal Article
ISSN: 0027-8424
Standard No.: 10.1073/pnas.160115697 doi
Subjects--Topical Terms: Alzheimer Disease--genetics Amino Acid Sequence Amino Acid Substitution--genetics Amyloid Precursor Protein Secretases Amyloid beta-Peptides--chemistry Amyloid beta-Protein Precursor--chemistry Arginine--genetics Aspartic Acid Endopeptidases--chemistry Binding Sites Cell Line Cloning, Molecular Endopeptidases Gene Expression Profiling Humans Hydrogen-Ion Concentration Molecular Sequence Data Mutation, Missense--genetics Nervous System--enzymology Netherlands Peptide Fragments--chemistry Phenylalanine--metabolism Protein Processing, Post-Translational RNA, Messenger--analysis Recombinant Fusion Proteins--chemistry Sequence Homology, Amino Acid Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Substrate Specificity Sweden