Farzan, M

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Aug 2000 - 9712-7 p. digital

Publication Type: Journal Article

0027-8424

10.1073/pnas.160115697 doi


Alzheimer Disease--genetics
Amino Acid Sequence
Amino Acid Substitution--genetics
Amyloid Precursor Protein Secretases
Amyloid beta-Peptides--chemistry
Amyloid beta-Protein Precursor--chemistry
Arginine--genetics
Aspartic Acid Endopeptidases--chemistry
Binding Sites
Cell Line
Cloning, Molecular
Endopeptidases
Gene Expression Profiling
Humans
Hydrogen-Ion Concentration
Molecular Sequence Data
Mutation, Missense--genetics
Nervous System--enzymology
Netherlands
Peptide Fragments--chemistry
Phenylalanine--metabolism
Protein Processing, Post-Translational
RNA, Messenger--analysis
Recombinant Fusion Proteins--chemistry
Sequence Homology, Amino Acid
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Substrate Specificity
Sweden