TY - GEN AU - Cao,S AU - Rustum,Y M TI - Synergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer: role of drug sequence and dose SN - 0008-5472 PY - 2000///0824 KW - Animals KW - Antimetabolites, Antineoplastic KW - administration & dosage KW - Antineoplastic Agents, Phytogenic KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Camptothecin KW - Colorectal Neoplasms KW - chemically induced KW - Dose-Response Relationship, Drug KW - Female KW - Fluorouracil KW - Irinotecan KW - Kinetics KW - Maximum Tolerated Dose KW - Neoplasm Transplantation KW - Rats KW - Rats, Inbred F344 KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -