Dinter, H <br/><br/>
The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents.  [electronic resource] 

 -  Journal of neuroimmunology  Aug 2000 
 - 136-46 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0165-5728 
<br/><br/><label>Standard No.: </label>10.1016/s0165-5728(00)00265-4  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors<br/>Acute Disease<br/>Animals<br/>Anti-Inflammatory Agents--pharmacology<br/>Cell Division--drug effects<br/>Cells, Cultured<br/>Central Nervous System--drug effects<br/>Chronic Disease<br/>Cyclic Nucleotide Phosphodiesterases, Type 4<br/>Dose-Response Relationship, Drug<br/>Down-Regulation--drug effects<br/>Encephalomyelitis, Autoimmune, Experimental--drug therapy<br/>Enzyme Inhibitors--pharmacology<br/>Female<br/>Humans<br/>Inflammation--drug therapy<br/>Interferon-gamma--biosynthesis<br/>Interleukin-5--biosynthesis<br/>Lymphocyte Activation--drug effects<br/>Mice<br/>Mice, Inbred Strains<br/>Multiple Sclerosis--drug therapy<br/>Oxazoles--pharmacology<br/>Rats<br/>Rats, Inbred Lew<br/>Recurrence<br/>Spleen--drug effects<br/>Substrate Specificity<br/>Th1 Cells--cytology<br/>Th2 Cells--cytology<br/>Tumor Necrosis Factor-alpha--metabolism