TY  - GEN
AU  - Barrow,J C
AU  - Nantermet,P G
AU  - Selnick,H G
AU  - Glass,K L
AU  - Rittle,K E
AU  - Gilbert,K F
AU  - Steele,T G
AU  - Homnick,C F
AU  - Freidinger,R M
AU  - Ransom,R W
AU  - Kling,P
AU  - Reiss,D
AU  - Broten,T P
AU  - Schorn,T W
AU  - Chang,R S
AU  - O'Malley,S S
AU  - Olah,T V
AU  - Ellis,J D
AU  - Barrish,A
AU  - Kassahun,K
AU  - Leppert,P
AU  - Nagarathnam,D
AU  - Forray,C
TI  - In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia
SN  - 0022-2623
PY  - 2000///0803
KW  - Adrenergic alpha-Antagonists
KW  - chemical synthesis
KW  - Animals
KW  - Biological Availability
KW  - Caco-2 Cells
KW  - Crystallography, X-Ray
KW  - Dogs
KW  - Humans
KW  - Male
KW  - Prostatic Hyperplasia
KW  - drug therapy
KW  - Pyrimidinones
KW  - Radioligand Assay
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptors, Adrenergic, alpha-1
KW  - drug effects
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm990612y
ER  -