TY - GEN AU - Ginsburg,A AU - Szczepanowski,R H AU - Ruvinov,S B AU - Nosworthy,N J AU - Sondej,M AU - Umland,T C AU - Peterkofsky,A TI - Conformational stability changes of the amino terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate: sugar phosphotransferase system produced by substituting alanine or glutamate for the active-site histidine 189: implications for phosphorylation effects SN - 0961-8368 PY - 2000///1103 KW - Alanine KW - chemistry KW - Amino Acid Substitution KW - Binding Sites KW - Calorimetry, Differential Scanning KW - Escherichia coli KW - enzymology KW - Glutamic Acid KW - Histidine KW - Models, Molecular KW - Phosphoenolpyruvate Sugar Phosphotransferase System KW - Phosphorylation KW - Phosphotransferases (Nitrogenous Group Acceptor) KW - Protein Conformation KW - Protein Denaturation KW - Thermodynamics N1 - Publication Type: Journal Article UR - https://doi.org/10.1110/ps.9.6.1085 ER -