TY  - GEN
AU  - Mayer,M P
AU  - Schröder,H
AU  - Rüdiger,S
AU  - Paal,K
AU  - Laufen,T
AU  - Bukau,B
TI  - Multistep mechanism of substrate binding determines chaperone activity of Hsp70
SN  - 1072-8368
PY  - 2000///0721
KW  - Adenosine Diphosphate
KW  - metabolism
KW  - Adenosine Triphosphatases
KW  - chemistry
KW  - Adenosine Triphosphate
KW  - Allosteric Site
KW  - drug effects
KW  - Bacterial Proteins
KW  - Catalytic Domain
KW  - Enzyme Activation
KW  - Escherichia coli
KW  - Escherichia coli Proteins
KW  - Genetic Complementation Test
KW  - HSP70 Heat-Shock Proteins
KW  - Heat-Shock Proteins
KW  - Hydrolysis
KW  - Kinetics
KW  - Models, Biological
KW  - Models, Molecular
KW  - Molecular Chaperones
KW  - Mutation
KW  - genetics
KW  - Phenotype
KW  - Protein Binding
KW  - Protein Structure, Secondary
KW  - Sigma Factor
KW  - Thermodynamics
KW  - Transcription Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/76819
ER  -