Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. [electronic resource]
- The Journal of biological chemistry Sep 2000
- 27694-702 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M004729200 doi
Animals Base Sequence Breast Neoplasms Cadmium--pharmacology Cell Line DNA-Binding Proteins--metabolism Enzyme Inhibitors--pharmacology Epithelial Cells--drug effects Female Flavonoids--pharmacology Gene Expression Regulation, Enzymologic--drug effects Gene Expression Regulation, Neoplastic--drug effects HeLa Cells Heme Oxygenase (Decyclizing)--genetics Heme Oxygenase-1 Humans L Cells Membrane Proteins Mice Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase 9 Mitogen-Activated Protein Kinases--metabolism Molecular Sequence Data NF-E2-Related Factor 2 Trans-Activators--metabolism Transcription Factors--metabolism Transcription, Genetic--drug effects Transcriptional Activation Tumor Cells, Cultured p38 Mitogen-Activated Protein Kinases