Runge, D

Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. [electronic resource] - Biochemical and biophysical research communications Jun 2000 - 333-41 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-291X

10.1006/bbrc.2000.2902 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--analysis
ATP-Binding Cassette Transporters--analysis
Aryl Hydrocarbon Hydroxylases
Blotting, Western
Cell Size--drug effects
Cells, Cultured
Cytochrome P-450 CYP1A1--biosynthesis
Cytochrome P-450 CYP1A2--biosynthesis
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2E1--metabolism
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--analysis
Enzyme Induction--drug effects
Epidermal Growth Factor--pharmacology
Hepatocyte Growth Factor--pharmacology
Humans
Isoenzymes--analysis
Liver--cytology
Methylcholanthrene--pharmacology
Mixed Function Oxygenases--biosynthesis
Multidrug Resistance-Associated Proteins
Neoplasm Proteins--genetics
Phenobarbital--pharmacology
RNA, Messenger--genetics
Rifampin--pharmacology
Steroid 16-alpha-Hydroxylase
Steroid Hydroxylases--metabolism
Vault Ribonucleoprotein Particles--genetics
beta-Naphthoflavone--pharmacology