Evans, T

Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats. [electronic resource] - Diabetes Apr 2000 - 662-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0012-1797

10.2337/diabetes.49.4.662 doi


Animals
Basement Membrane--pathology
Bosentan
Capillaries--pathology
Collagen--genetics
Diabetes Mellitus, Experimental--metabolism
Endothelin Receptor Antagonists
Extracellular Matrix--metabolism
Fibronectins--genetics
Galactose--pharmacology
Gene Expression
Male
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Receptors, Endothelin--physiology
Retina--ultrastructure
Retinal Vessels--pathology
Sulfonamides--pharmacology