TY - GEN AU - Beltinger,C AU - Fulda,S AU - Kammertoens,T AU - Uckert,W AU - Debatin,K M TI - Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis SN - 0008-5472 PY - 2000///0720 KW - Anti-Bacterial Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Bongkrekic Acid KW - Cell Nucleus KW - Cell-Free System KW - Chloramphenicol KW - Cytochrome c Group KW - metabolism KW - Cytosol KW - DNA Damage KW - DNA Fragmentation KW - Dose-Response Relationship, Drug KW - Enzyme Activation KW - Flow Cytometry KW - Ganciclovir KW - Genetic Therapy KW - methods KW - Humans KW - Membrane Potentials KW - Mitochondria KW - Proto-Oncogene Proteins c-bcl-2 KW - Simplexvirus KW - enzymology KW - Thymidine Kinase KW - Time Factors KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -