Li, D N <br/><br/>
Polymorphisms in P450 CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol.  [electronic resource] 

 -  Pharmacogenetics  Jun 2000 
 - 343-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0960-314X 
<br/><br/><label>Standard No.: </label>10.1097/00008571-200006000-00008  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alleles<br/>Aryl Hydrocarbon Hydroxylases<br/>Base Sequence<br/>Carcinogens--metabolism<br/>Cytochrome P-450 CYP1B1<br/>Cytochrome P-450 Enzyme System--genetics<br/>DNA Primers<br/>DNA, Complementary<br/>Dihydroxydihydrobenzopyrenes--pharmacokinetics<br/>Estradiol--analogs & derivatives<br/>Estrogens, Catechol<br/>Ethanolamines--pharmacokinetics<br/>Humans<br/>Hydroxylation<br/>Kinetics<br/>Mutagenesis, Site-Directed<br/>Oxazines--pharmacokinetics<br/>Polymorphism, Genetic