Lewis, D F

On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics: towards the prediction of human p450 substrate specificity and metabolism. [electronic resource] - Biochemical pharmacology Aug 2000 - 293-306 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2952

10.1016/s0006-2952(00)00335-x doi


Animals
Binding Sites
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--metabolism
Enzyme Inhibitors--pharmacology
Humans
Isoenzymes--antagonists & inhibitors
Metabolic Clearance Rate
Microsomes--enzymology
Models, Chemical
Pharmaceutical Preparations--metabolism
Structure-Activity Relationship
Substrate Specificity