Li, T K <br/><br/>
Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions.  [electronic resource] 

 -  Biochemistry  Jun 2000 
 - 7107-16 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0006-2960 
<br/><br/><label>Standard No.: </label>10.1021/bi000171g  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antioxidants--pharmacology<br/>Berberine Alkaloids--chemistry<br/>DNA--chemistry<br/>DNA Topoisomerases, Type I--chemistry<br/>DNA Topoisomerases, Type II--chemistry<br/>Humans<br/>Intercalating Agents--chemistry<br/>Models, Molecular<br/>Molecular Structure<br/>Nucleic Acid Conformation--drug effects<br/>Nucleic Acid Denaturation--drug effects<br/>Protein Binding<br/>Temperature<br/>Thermodynamics<br/>Viscosity