Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. [electronic resource]
- Blood Jun 2000
- 3929-38 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
Acute Disease Adult Aged Aged, 80 and over Apoptosis--drug effects Bone Marrow Cells--drug effects Cell Division--drug effects Cells, Cultured Cytarabine--toxicity Female Genes, bcl-2 HL-60 Cells Humans Leukemia, Myeloid Liposomes Male Middle Aged Oligodeoxyribonucleotides, Antisense--pharmacology Proto-Oncogene Proteins c-bcl-2--metabolism Tumor Cells, Cultured