TY  - GEN
AU  - Owen,M R
AU  - Doran,E
AU  - Halestrap,A P
TI  - Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
SN  - 0264-6021
PY  - 2000///0803
KW  - Animals
KW  - Electron Transport
KW  - drug effects
KW  - Electron Transport Complex I
KW  - Gluconeogenesis
KW  - Hypoglycemic Agents
KW  - pharmacology
KW  - Liver
KW  - Male
KW  - Metformin
KW  - Mitochondria
KW  - NADH, NADPH Oxidoreductases
KW  - antagonists & inhibitors
KW  - Rats
KW  - Rats, Wistar
KW  - Signal Transduction
KW  - Submitochondrial Particles
KW  - enzymology
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ER  -