TY - GEN AU - Kataoka,T AU - Budd,R C AU - Holler,N AU - Thome,M AU - Martinon,F AU - Irmler,M AU - Burns,K AU - Hahne,M AU - Kennedy,N AU - Kovacsovics,M AU - Tschopp,J TI - The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways SN - 0960-9822 PY - 2000///0802 KW - Apoptosis KW - CASP8 and FADD-Like Apoptosis Regulating Protein KW - CD3 Complex KW - physiology KW - Carrier Proteins KW - metabolism KW - Caspase 8 KW - Caspase 9 KW - Caspase Inhibitors KW - Cells, Cultured KW - Fas Ligand Protein KW - Humans KW - Interleukin-2 KW - biosynthesis KW - Intracellular Signaling Peptides and Proteins KW - Membrane Glycoproteins KW - pharmacology KW - Mitogen-Activated Protein Kinases KW - NF-kappa B KW - Proteins KW - Proto-Oncogene Proteins c-raf KW - Receptor-Interacting Protein Serine-Threonine Kinases KW - Receptors, Tumor Necrosis Factor KW - Signal Transduction KW - drug effects KW - T-Lymphocytes KW - TNF Receptor-Associated Factor 1 KW - TNF Receptor-Associated Factor 2 KW - Transcription Factor AP-1 KW - fas Receptor N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s0960-9822(00)00512-1 ER -