The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. [electronic resource]
- Current biology : CB Jun 2000
- 640-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0960-9822
10.1016/s0960-9822(00)00512-1 doi
Apoptosis CASP8 and FADD-Like Apoptosis Regulating Protein CD3 Complex--physiology Carrier Proteins--metabolism Caspase 8 Caspase 9 Caspase Inhibitors Cells, Cultured Fas Ligand Protein Humans Interleukin-2--biosynthesis Intracellular Signaling Peptides and Proteins Membrane Glycoproteins--pharmacology Mitogen-Activated Protein Kinases--metabolism NF-kappa B--metabolism Proteins--metabolism Proto-Oncogene Proteins c-raf Receptor-Interacting Protein Serine-Threonine Kinases Receptors, Tumor Necrosis Factor--physiology Signal Transduction--drug effects T-Lymphocytes--drug effects TNF Receptor-Associated Factor 1 TNF Receptor-Associated Factor 2 Transcription Factor AP-1--metabolism fas Receptor--physiology