TY - GEN AU - Colombel,J F AU - Ferrari,N AU - Debuysere,H AU - Marteau,P AU - Gendre,J P AU - Bonaz,B AU - Soulé,J C AU - Modigliani,R AU - Touze,Y AU - Catala,P AU - Libersa,C AU - Broly,F TI - Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy SN - 0016-5085 PY - 2000///0621 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Alleles KW - Azathioprine KW - administration & dosage KW - Bone Marrow KW - drug effects KW - Crohn Disease KW - drug therapy KW - DNA Mutational Analysis KW - Female KW - Gene Expression Regulation, Enzymologic KW - Genotype KW - Homozygote KW - Humans KW - Immunosuppressive Agents KW - Leukocyte Count KW - Leukopenia KW - chemically induced KW - Male KW - Methyltransferases KW - genetics KW - Middle Aged KW - Mutation KW - Phenotype KW - Polymerase Chain Reaction KW - Polymorphism, Single-Stranded Conformational KW - Thrombocytopenia N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/s0016-5085(00)70354-4 ER -