Colombel, J F

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. [electronic resource] - Gastroenterology Jun 2000 - 1025-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0016-5085

10.1016/s0016-5085(00)70354-4 doi


Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Azathioprine--administration & dosage
Bone Marrow--drug effects
Crohn Disease--drug therapy
DNA Mutational Analysis
Female
Gene Expression Regulation, Enzymologic--drug effects
Genotype
Homozygote
Humans
Immunosuppressive Agents--administration & dosage
Leukocyte Count
Leukopenia--chemically induced
Male
Methyltransferases--genetics
Middle Aged
Mutation
Phenotype
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Thrombocytopenia--chemically induced