TY - GEN AU - Hoepping,A AU - Johnson,K M AU - George,C AU - Flippen-Anderson,J AU - Kozikowski,A P TI - Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter SN - 0022-2623 PY - 2000///0629 KW - Animals KW - Carrier Proteins KW - antagonists & inhibitors KW - Corpus Striatum KW - ultrastructure KW - Cyclization KW - Dopamine KW - metabolism KW - Dopamine Plasma Membrane Transport Proteins KW - Heterocyclic Compounds, 3-Ring KW - chemical synthesis KW - Membrane Glycoproteins KW - Membrane Transport Proteins KW - Mesencephalon KW - Molecular Conformation KW - Nerve Tissue Proteins KW - Norepinephrine KW - Norepinephrine Plasma Membrane Transport Proteins KW - Occipital Lobe KW - Parietal Lobe KW - Rats KW - Serotonin KW - Serotonin Plasma Membrane Transport Proteins KW - Structure-Activity Relationship KW - Symporters KW - Synaptosomes KW - Tritium KW - Tropanes KW - chemistry N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/jm0001121 ER -