Ogiso, Y
Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs. [electronic resource]
- Cancer research May 2000
- 2429-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 0008-5472
Subjects--Topical Terms: Acetylcysteine--analogs & derivatives Animals Antigens, Neoplasm Antineoplastic Agents--pharmacology Antineoplastic Agents, Phytogenic--pharmacology Blotting, Northern Cell Cycle--drug effects Cysteine Endopeptidases--metabolism Cysteine Proteinase Inhibitors--pharmacology DNA Topoisomerases, Type II--biosynthesis DNA-Binding Proteins Dose-Response Relationship, Drug Doxorubicin--pharmacology Etoposide--pharmacology Glucose--metabolism Humans Hypoxia Immunoblotting Isoenzymes--antagonists & inhibitors Methotrexate--pharmacology Mice Mice, Nude Multienzyme Complexes--metabolism Neoplasm Transplantation Nucleic Acid Synthesis Inhibitors--pharmacology Proteasome Endopeptidase Complex Time Factors Topoisomerase II Inhibitors Tumor Cells, Cultured Vincristine--pharmacology