Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Oct 1976
- 3381-5 p. digital
Publication Type: Journal Article
0027-8424
10.1073/pnas.73.10.3381 doi
Animals Benzopyrenes--metabolism Cytochrome P-450 Enzyme System--metabolism In Vitro Techniques Kinetics Methylcholanthrene--pharmacology Microsomes, Liver--drug effects Mixed Function Oxygenases--metabolism Phenobarbital--pharmacology Rats Stereoisomerism