Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction. [electronic resource]
- The Journal of biological chemistry May 2000
- 14632-41 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.275.19.14632 doi
Cell Line Connective Tissue Growth Factor Cysteine-Rich Protein 61 DNA, Complementary Extracellular Matrix Proteins--genetics Factor VIIa--physiology Gene Expression Regulation--physiology Growth Substances--genetics Humans Immediate-Early Proteins--genetics Intercellular Signaling Peptides and Proteins Kinetics RNA, Messenger--genetics Signal Transduction Thrombin--physiology Transcription, Genetic Transcriptional Activation