TY  - GEN
AU  - Busby,E C
AU  - Leistritz,D F
AU  - Abraham,R T
AU  - Karnitz,L M
AU  - Sarkaria,J N
TI  - The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1
SN  - 0008-5472
PY  - 2000///0511
KW  - Alkaloids
KW  - pharmacology
KW  - Antineoplastic Agents
KW  - Cell Cycle Proteins
KW  - metabolism
KW  - Checkpoint Kinase 1
KW  - Checkpoint Kinase 2
KW  - DNA Damage
KW  - drug effects
KW  - G2 Phase
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - K562 Cells
KW  - Models, Biological
KW  - Phosphorylation
KW  - Phosphoserine
KW  - Protein Kinase Inhibitors
KW  - Protein Kinases
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Radiation-Sensitizing Agents
KW  - Signal Transduction
KW  - Staurosporine
KW  - analogs & derivatives
KW  - cdc25 Phosphatases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -