Philippart, P <br/><br/>
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Apr 2000 
 - 1557-62 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1078-0432 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Biopsy<br/>Camptothecin--analogs & derivatives<br/>Cell Division--drug effects<br/>Colon--drug effects<br/>Colonic Neoplasms--drug therapy<br/>Culture Techniques<br/>DNA Topoisomerases, Type I--metabolism<br/>Dose-Response Relationship, Drug<br/>Doxorubicin--pharmacology<br/>Enzyme Inhibitors--pharmacology<br/>Etoposide--pharmacology<br/>Humans<br/>Irinotecan<br/>Thymidine--metabolism<br/>Topoisomerase I Inhibitors<br/>Topotecan--pharmacology<br/>Tritium<br/>Tumor Cells, Cultured