Domanski, T L <br/><br/>
Dual role of human cytochrome P450 3A4 residue Phe-304 in substrate specificity and cooperativity.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  May 2000 
 - 585-91 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aryl Hydrocarbon Hydroxylases<br/>Benzoflavones--metabolism<br/>Binding Sites<br/>Cloning, Molecular<br/>Cytochrome P-450 CYP3A<br/>Cytochrome P-450 Enzyme System--chemistry<br/>Humans<br/>Hydroxylation<br/>Kinetics<br/>Mixed Function Oxygenases--chemistry<br/>Models, Molecular<br/>Mutation--genetics<br/>Oxidation-Reduction<br/>Phenylalanine--chemistry<br/>Progesterone--metabolism<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Steroid Hydroxylases--metabolism<br/>Substrate Specificity