TY  - GEN
AU  - Wellington,C L
AU  - Singaraja,R
AU  - Ellerby,L
AU  - Savill,J
AU  - Roy,S
AU  - Leavitt,B
AU  - Cattaneo,E
AU  - Hackam,A
AU  - Sharp,A
AU  - Thornberry,N
AU  - Nicholson,D W
AU  - Bredesen,D E
AU  - Hayden,M R
TI  - Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
SN  - 0021-9258
PY  - 2000///0810
KW  - Amino Acid Sequence
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Binding Sites
KW  - Blotting, Western
KW  - Carcinogens
KW  - pharmacology
KW  - Caspase 3
KW  - Caspase 6
KW  - Caspase Inhibitors
KW  - Caspases
KW  - metabolism
KW  - Cell Line
KW  - Enzyme Activation
KW  - genetics
KW  - Fluorescent Antibody Technique
KW  - Humans
KW  - Huntingtin Protein
KW  - Molecular Sequence Data
KW  - Mutagenesis
KW  - Nerve Tissue Proteins
KW  - Neurons
KW  - Nuclear Proteins
KW  - Peptides
KW  - Plasmids
KW  - Rats
KW  - Tamoxifen
KW  - Time Factors
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M001475200
ER  -