TY  - GEN
AU  - Zhang,S
AU  - Wilson,D B
AU  - Ganem,B
TI  - Probing the catalytic mechanism of prephenate dehydratase by site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain
SN  - 0006-2960
PY  - 2000///0601
KW  - Amino Acid Substitution
KW  - genetics
KW  - Bacterial Proteins
KW  - chemistry
KW  - Binding Sites
KW  - Calorimetry
KW  - Catalysis
KW  - drug effects
KW  - Chorismate Mutase
KW  - Chromatography, Gel
KW  - Circular Dichroism
KW  - Conserved Sequence
KW  - Cyclohexanecarboxylic Acids
KW  - metabolism
KW  - Cyclohexenes
KW  - Escherichia coli
KW  - enzymology
KW  - Escherichia coli Proteins
KW  - Feedback
KW  - Fluorescence
KW  - Kinetics
KW  - Multienzyme Complexes
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Phenylalanine
KW  - Prephenate Dehydratase
KW  - antagonists & inhibitors
KW  - Protein Structure, Tertiary
KW  - Structure-Activity Relationship
KW  - Thermodynamics
KW  - Titrimetry
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/bi9926680
ER  -