Li, M

Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. [electronic resource] - Science (New York, N.Y.) Apr 2000 - 335-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0036-8075

10.1126/science.288.5464.335 doi


Amino Acid Chloromethyl Ketones--administration & dosage
Amino Acid Substitution
Amyotrophic Lateral Sclerosis--drug therapy
Animals
Apoptosis--drug effects
Caspase 1--genetics
Caspase 3
Caspase Inhibitors
Caspases--genetics
Cysteine Proteinase Inhibitors--administration & dosage
Disease Models, Animal
Disease Progression
Enzyme Activation
Gene Expression Regulation, Enzymologic
Humans
Injections, Intraventricular
Interleukin-1--metabolism
Male
Mice
Mice, Transgenic
Motor Neurons--drug effects
Nerve Degeneration
Neuroprotective Agents--administration & dosage
Psychomotor Performance
Spinal Cord--enzymology
Superoxide Dismutase--genetics
Superoxide Dismutase-1