ERK1 and ERK2 activation by chemotactic factors in human eosinophils is interleukin 5-dependent and contributes to leukotriene C(4) biosynthesis. [electronic resource]
- The Journal of biological chemistry Apr 2000
- 10968-75 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.275.15.10968 doi
Adaptor Proteins, Signal Transducing Butadienes--pharmacology Chemokine CCL5--pharmacology Dose-Response Relationship, Drug Eosinophils--drug effects Flavonoids--pharmacology GRB2 Adaptor Protein Humans Interleukin-5--pharmacology Interleukin-8--pharmacology Leukotriene C4--biosynthesis Mitogen-Activated Protein Kinase 1--physiology Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases--physiology N-Formylmethionine Leucyl-Phenylalanine--pharmacology Nitriles--pharmacology Phosphorylation Proteins--physiology