TY - GEN AU - Goodkin,D E AU - Shulman,M AU - Winkelhake,J AU - Waubant,E AU - Andersson,P AU - Stewart,T AU - Nelson,S AU - Fischbein,N AU - Coyle,P K AU - Frohman,E AU - Jacobs,L AU - Holcenberg,J AU - Lee,M AU - Mocci,S TI - A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis SN - 0028-3878 PY - 2000///0504 KW - Adult KW - Autoantibodies KW - blood KW - Brain KW - pathology KW - Dose-Response Relationship, Immunologic KW - Double-Blind Method KW - Female KW - HLA Antigens KW - immunology KW - HLA-DR2 Antigen KW - Humans KW - Immunotherapy KW - Interferon-gamma KW - metabolism KW - Magnetic Resonance Imaging KW - Male KW - Middle Aged KW - Multiple Sclerosis, Chronic Progressive KW - Myelin Basic Protein KW - adverse effects KW - Myelin Proteins KW - Myelin-Associated Glycoprotein KW - Myelin-Oligodendrocyte Glycoprotein KW - Peptide Fragments KW - T-Lymphocytes KW - Treatment Outcome KW - Vaccines, Conjugate N1 - Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1212/wnl.54.7.1414 ER -